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Police reported activity overnight at Vice President JD Vance's Cincinnati home.
Video footage from the scene showed apparent damage to the windows, possibly caused by vandalism or a break-in attempt.
The Secret Service has not commented.
Vance was home for the New Year's holiday in the East Walnut Hills area but returned to Washington, D.C. on Sunday.
Local police say a suspect is in custody, but no further details are available.