The Cavaliers lost in heartbreaking fashion to the Rockets 109-108 from Houston.
Darius Garland went to the free throw line for three attempts on a flagrant which could have given Cleveland the lead with 2.1 seconds left.
However, he failed on two-of-three and Donovan Mitchell missed a three-pointer to end the game.
The Cavs fell to 36-and-7 and will visit the 76ers tomorrow night.