The Cavaliers pulled away from the Chicago Bulls in the final minute of their 108-105 win at Rocket Mortgage FieldHouse.
The game was tied at 103 with 45 seconds left in regulation before the Cavs hit all five of their free throws down the stretch.
Coby White missed a game-tying three at the buzzer for Chicago.
Donovan Mitchell had 30 points in the victory. The Cavs have won 10 of their last 11 to improve to 36-and-17.
They now head into the All-Star break and will return to action at home against the Orlando Magic next Thursday.